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Caretakers of surgical patients in health systems are sometimes confronted with the dilemma of deciding whether to warm irrigation fluids for intraoperative use in order to prevent the risk of postsurgical hypothermia or to use these fluids at room temperature.
Although the jury is still out as far as providing a definitive answer to the question, the majority of published reports support the use of warm irrigation fluids to minimize the risk of hypothermia. Perioperative hypothermia is an unintentional drop in core body temperature Causes of postoperative hypothermia are numerous and include use of anesthetic agents, exposure of internal organs, ambient environment in the operating room, and the temperature and volume of irrigation fluids.
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IV therapy permits rapid control of HR and contractility.
Administration: IVPB in 50 ml or more of D5W or normal saline over 5 minutes or longer. (Total=6 tabs) If received later in the day, may take all 6 tablets at once or in divided doses. The dilutions listed are conservative guidelines that can be used in non-acute conditions.
Day#2: 1 tab before breakfast, 1 tab after lunch & dinner, and 2 tablets at bedtime. Day#4: 1 tab before breakfast, after lunch and at bedtime. The infusion times were formulated to mimic the onset of an oral formulation. Oral to IV conversion (2.5 to 1) : eg 50mg oral=20mg IV (equivalent beta-blockade).
The American Medical Association has questioned whether expiration dating markedly underestimates the actual shelf life of drug products.
Results from the shelf life extension program (SLEP) have been evaluated to provide extensive data to address this issue.